Association of pyrethroid exposure with behavioural skills in children


The associations between prenatal and childhood exposure to pyrethroid incesticides and children’s behaviour were assessed in the PELAGIE mother-child cohort by Viel et al., 2017. Five pyrethroid metabolites (3-PBA, 4-F-3-PBA, cis-DCCA and trans-DCCA, and cis-DBCA) were measured in maternal and child urine samples and children’s behaviour was assessed using the Strengths and Difficulties Questionnaire (SDQ). It was shown that childhood 3-PBA concentrations were associated with externalising difficulties and increased prenatal cis-DCCA concentrations were associated with internalising difficulties. This study suggests that exposure to certain pyrethroids, even at environmental levels, during pregnancy and childhood, may affect the neurobehavioral development of children.

More info: